This formulation combines high-potency amounts of the active forms of vitamin B12 and folate in a convenient lozenge. Both of these water-soluble B-vitamins work together and need to be supplied in the diet in adequate amounts to support nervous system function and help maintain the normal metabolism of homocysteine, a potentially toxic amino acid metabolite that damages arteries.
Absorption of vitamin B12 is facilitated by intrinsic factor, a natural protein produced by the parietal cells of the stomach lining. B12 can also be absorbed by an alternate mechanism that does not rely on intrinsic factor when high-potency amounts of 1,000 mcg or more are taken. This product provides 1,000 mcg of vitamin B12 so that individuals without adequate intrinsic factor can enhance their intake of this essential B vitamin through oral supplementation.
Vitamin B12 as methylcobalamin: Vitamin B12 is crucial to the formation of healthy red blood cells, energy production, nervous system support, cognitive function, and homocysteine regulation. Although cyanocobalamin is the most commonly used form of vitamin B12 in dietary supplements, it must be converted by enzymes into an active coenzyme form to be useful. Nutritional inadequacies, enzyme defects, and tissue abnormalities can reduce the body’s ability to synthesize the active forms of B12. In contrast, vitamin B12 as methylcobalamin is a “body-ready” form with metabolic benefits that may not be provided by other forms of vitamin B12. It appears that methylcobalamin may be particularly useful for individuals with impaired methylation capacity, including those with elevated homocysteine or neurological impairments.
Active form of folate: This B-vitamin is crucial for generating red blood cells, regulating homocysteine metabolism, assisting DNA repair, and supporting neurological processes. Metafolin®* L-5-methyltetrahydrofolate (L-5-MTHF), an active form of folate, is included in this product to help ensure more immediate effects on metabolism compared to folic acid, the form of folate commonly used in fortified foods and supplements.
These tablets are sweetened naturally with mannitol and are free of added flavorings. The tablets dissolve in the mouth within a few minutes or may also be swallowed whole if desired. However, this supplement may be better absorbed when slowly dissolved under the tongue rather than swallowed whole. Individuals who have an increased risk for vitamin B12/folate deficiency are the elderly, vegetarians, and individuals with ulcers, Crohn’s disease, bacterial overgrowth, and other gastrointestinal disorders. This dietary supplement may be useful for individuals who may have difficulty absorbing vitamin B12 and folate and are looking for a safe and efficient method to enhance their supply of these bioactive forms of nutrients. This product is free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten, yeast, and soybeans. Contains no artificial colors, flavors, or preservatives.
Suggested Use: 1 tablet daily with food.
This product was made in a GMP and ISO 9001:2008 registered facility.